We work on many aspects of mathematical and computational modeling of cancer evolution, cancer cell biology, and cancer ecology. We are particularly fascinated by cancer-stroma and cancer-immune system interactions. Some of our current focus areas are to uncover the laws of selection and progression in hematopoietic malignancies, the complex dynamics and cellular kinetics during CAR-T cell therapy, quantifying geospatial cellular distributions from digital pathology data, and novel ways to measure and understand cancer heterogeneity.

We closely collaborate with a number of amazing research groups at Moffitt: Noemi Andor, Karen Mann, Andriy Marusyk, David Basanta, Frederick Locke, Brandon Manley and Eric Padron, as well as with Meghan Ferrall-Fairbanks at UF and Christian Brendel at Harvard University.