Patent and Patent Applications (Independent Research)

Patent Applications
  • Ji, Haitao. Preparation of small-molecule inhibitors for the β-catenin/b-cell lymphoma 9 protein-protein interaction. PCT International Application, 2020, WO2021055936 A1.
  • Cai, Jianfeng; Sang, Peng; Shi, Yan; Ji, Haitao; Zhang, Min. Preparation of β-catenin/B-cell lymphoma 9 protein–protein interaction inhibiting peptidomimetics for treating cancers. PCT International Application, 2020, WO2020219819 A1.
  • List, Alan; Ji, Haitao; Luca, Vince. Structure-guided engineering of peptide-based NLRP3 inflammasome inhibitors for myelodysplastic syndromes. PCT International Application, 2020, WO2020223595 A1.
  • Ji, Haitao. Preparation of peptidomimetics as inhibitors of β-catenin/TCF protein-protein interaction useful in treating cancers. PCT International Application, 2020, WO2020118179 A1.
  • Ji, Haitao. N-Aroylpiperazine derivatives as β-catenin and BCL9 inhibitors and their preparation. PCT International Application, 2020, WO2020081918 A1.
  • List, Alan; Ji, Haitao. Stapled peptides as pyrin-domain targeted NLRP3 inflammasome inhibitors. PCT International Application, 2020, WO2020037119 A1.
  • Ji, Haitao. Preparation of substituted indoles as inhibitors for the β-catenin/t-cell factor protein-protein interaction. PCT International Application, 2019, WO2019191410 A1.
  • Ji, Haitao. Preparation of substituted quinolines as inhibitors for the β-catenin/B-cell lymphoma 9 (BCL9) protein–protein interaction. PCT International Application, 2019, WO2019118961 A1.
  • Ji, Haitao. Inhibitors for the β-catenin/B-cell lymphoma 9 (BCL9) protein–protein interaction. PCT International Application, 2019, WO2019139961 A1.
  • Ji, Haitao; Zhang, Min. Methods and composition of 4-substituted benzoylpiperazine-1-substituted carbonyls as beta-catenin/B-cell lymphoma 9 inhibitors. PCT International Application, 2017, WO2017165839 A1
  • Ji, Haitao; Zhang, Yongqiang; Zhang, Min; Catrow, J. Leon.Methods and compositions of substituted 5H[1,2,5]oxadiazolo[3',4':5,6]pyrazino[2,3-B]indole analogs as inhibitors of beta-catenin/T-cell factor protein–protein interactions. PCT International Application 2016, WO2016187050 A1, US20180134729A1
  • Ji, Haitao; Logan, R. Hoggard, Yongqiang Zhang, John A. Wisniewski.Substituted N-([1,1'-biphenyl]-3-yl)-[1,1'-biphenyl]-3-carboxamide analogues as inhibitors for β-catenin/B-cell lymphoma 9 interactions. PCT International Application 2016, WO2016168524 A1, US20180092866A1.
Granted Patent
  • Ji, Haitao; Yu, Binxun; Zhang, Min; Guo, Wenxing. Substituted 1H-indazol-1-ol analogs as inhibitors of β-catenin/Tcf protein-protein interactions. . S. Patent 9,738,628 B2 (August 22, 2017).
  • Ji, Haitao; Zhang, Yongqiang; Zhang, Min; Catrow, J. Leon. Methods and compositions of substituted 5H[1,2,5]oxadiazolo[3',4':5,6]pyrazino[2,3-B]indole analogs as inhibitors of beta-catenin/T-cell factor protein–protein interactions. U. S. Patent 10,273,246 B2 (April 30, 2019).

 

Patents and Patent Application (Postdoctoral)

Granted Patents
  • Meyskens, Frank L. Jr.; Silverman, Richard B.; Yang, Sun; Ji, Haitao; Xue, Fengtian; Poulos, Thomas L. Specific nNOS inhibitors for the therapy and prevention of human melanoma. U. S. Patent 8,642,282 (Granted on Feb. 4, 2014).
  • Silverman, Richard B.; Ji, Haitao; Huang, He. Novel Monocationic Compounds to Selectively Inhibit Neuronal Nitric Oxide Synthase. U. S. Patent 8,557,552 (Granted on Oct. 15, 2013).
  • Silverman, Richard B.; Ji, Haitao; Lawton, Graham R. Potent and highly selective heteroaromatic inhibitors of neuronal nitric oxide synthase (nNOS). U. S. Patent 7,994,326 B2 (Granted on Aug. 9, 2011).
  • Silverman, Richard B.; Ji, Haitao. Heteroaromatic selective inhibitors of neuronal nitric oxide synthase. U. S. Patents 7,470,790 and 8,158,658 (Granted on Dec. 30, 2008).