Stromal reactivity deferentially drives tumor cell evolution and prostate cancer progression
Frankenstein Z, Basanta D, Franco OE, Gao Y, Javier RA, Strand DW, Lee MJ, Hayward SW, Ayala G, Anderson RA
[bioRxiv][blog]
Cancer associated fibroblasts and alectinib switch the evolutionary games that non-small cell lung cancer plays
Kaznatcheev A, Peacock J, Basanta D, Marusyk A, Scott JG
[bioRxiv]
The influence of cellular characteristics on the evolution of shape homeostasis
Gerlee P, Basanta D, Anderson ARA
Artif Life 2017 23(3):424-448 [link][arXiv]
Evolutionary emergence of angiogenesis in avascular tumors using a spatial public good games
Salimi Sartakhti J, Manshaei MH, Basanta D, Sadegui M.
PLOS One 2017 11;12(4):e0175063 [link]
Homeostasis back and forth: an ecoevolutionary perspective of cancer
Basanta D, Anderson AR
Cold Spring Harb Perspect Med a028332 [link][bioRxiv]
Cancer treatment scheduling and dynamic heterogeneity in social dilemmas of tumor acidity and vascularity
Kaznatcheev A, Vander Velde R, Scott JG, Basanta D
Br J Cancer 2017 14;116(6):785-792 [link]
Predictive Computational Modeling to define effective treatment strategies for bone metastatic prostate cancer
Cook LM, Araujo A, Pow-Sang JM, Budzevich MM, Basanta D, Lynch CC
Sci Rep. 2016 14;6;29384 [link]
Edge effects in game-theoretic dynamics of spatially structured tumours
Kaznatcheev A, Scott JG, Basanta D
J R Soc Interface. 2015 Jul 6;12(108). pii: 20150154. doi: 10.1098/rsif.2015.0154. PMID 26040596. [link][bioRxiv][blog]
Evolutionary game theory: cells as players
Hummert S, Bohl K, Basanta D, Deutsch A, Werner S, Theissen G, Schroeter A, Schuster S
Mol Biosyst. 2014 Dec;10(12):3044-65. doi: 10.1039/c3mb70602h. PMID: 25270362
Current and emerging therapies for bone metastatic castration-resistant prostate cancer
Frieling JS, Basanta D, Lynch CC
Cancer Control. 2015 Jan;22(1):109-20. PMID: 25504285
Evolutionary game theory: molecules as players
Bohl K1, Hummert S, Werner S, Basanta D, Deutsch A, Schuster S, Theißen G, Schroeter A
Mol Biosyst. 2014 Oct 28;10(12):3066-74
Invasion and proliferation kinetics in enhancing gliomas predict IDH1 mutation status
Baldock AL, Yagle K, Born DE, Ahn S, Trister AD, Neal M, Johnston SK, Bridge CA, Basanta D, Scott J, Malone H, Sonabend AM, Canoll P, Mrugala MM, Rockhill JK, Rockne RC, Swanson KR
Neuro Oncol. 2014 Jun;16(6):779-86
Improving Treatment Strategies for Patients with Metastatic Castrate Resistant Prostate Cancer Through Personalized Computational Modeling
Gallaher J, Cook L, Gupta S, Araujo A, Dhillon J, Park J, Scott J, Pow-Sang JM, Basanta D, Lynch C
Clin Exp Metastasis, August 2014 [link][blog]
An Integrated Computational Model of the Bone Microenvironment in Bone-Metastatic Prostate Cancer
Araujo, A, Cook, L, Lynch, C, Basanta D
Cancer Research May 1 2014 74;2391 [link][blog]
Microenvironmental variables must influence intrinsic phenotypic parameters of cancer stem cells to affect tumourigenenicity
Scott J, Hjelmeland A, Chinnaiyan P, Anderson ARA, Basanta D
PLOS Computational Biology 2014 10(1) e1003433
Senescent fibroblasts in melanoma initiation and progression: an integrated theoretical, experimental, and clinical approach
Kim E, Rebecca VW, Fedorenko IV, Messina JL, Mathew R, Maria-Engler SS, Basanta D, Smalley KS, Anderson ARA
Cancer Research Dec 1 2013 73;6874
Exploiting ecological principles to better understand cancer progression and treatment
Basanta D, Anderson ARA
Interface Focus 6 v3 4 2013 [link][blog]
A mathematical model of tumour selfseeding reveals secondary metastatic deposits as drivers of primary tumour growth
Scott J, Basanta D, Anderson ARA, Gerlee P
J. R. Soc. 6 v10 82 (2013)
Investigating prostate cancer tumour–stroma interactions: clinical and biological insights from an evolutionary game
Basanta D, Scott J. G., Fishman M N, Ayala G, Hayward S, Anderson ARA
British Journal of Cancer. 106, 174-81 (2012)
Exploiting evolution to treat drug resistance: combination therapy and the double bind
Basanta D, Gatenby RA, Anderson ARA
Mol Pharm. 2012 Apr 2;9(4):914-21 PMCID: PMC3325107 (2012)
Production of 2-hydroxyglutarate by isocitrate dehydrogenase 1-mutated gliomas: an evolutionary alternative to the Warburg shift?
Scott JG, Basanta D, Chinnaiyan P, Canoll P, Swanson KR, Anderson ARA
Neuro Oncol. 13 (12) 1262-64 (2011)
Evolving homeostatic tissue using genetic algorithms
Gerlee P, Basanta D, Anderson ARA
Prog Biophys Mol Biol. Aug;106(2):414-25. PMID: 21419156 (2011)
The role of IDH1 mutated tumour cells in secondary glioblastomas: an evolutionary game theoretical view
Basanta D, Scott J, Rockne R, Swanson K, Anderson ARA
Physical Biology (2011)
‘Go or Grow’: the key to the emergence of invasion in tumour progression?
Hatzikirou H, Basanta D, Simon M, Schaller K, Deutsch A
Math Med Biol (2010) PMID: 20610469
Computational analysis of the influence of microenvironment on carcinogenesis
Basanta D, Ribba B, Watkin E, You B, Deutsch A
Jan;229(1):22-9. Epub 2010 Oct 31. PMID: 21044636
Microenvironmental independence associated with tumor progression
Anderson AR, Hassanein M, Branch KM, Lu J, Lobdell NA, Maier J, Basanta D, Weidow B, Narasanna A, Arteaga CL, Reynolds AB, Quaranta V, Estrada L, Weaver AM
Cancer Res. 2009 Nov 15;69(22):8797-806 PMCID: PMC2783510
The role of TGF-β mediated tumor-stroma interactions in prostate cancer progression: an integrative approach
Basanta D, Strand D, Lukner R, Franco O, Ayala G, Cliffel D, Hayward S, Anderson ARA
Cancer Research, Cancer Res. 2009 Sep 1;69 (17):7111-20. Epub 2009 Aug 25. PMCID: PMC2748342
Perspectives on Tissue Interactions in Development and Disease
Strand D, Franco O, Basanta D, Anderson ARA, Hayward S
Curr. Mol. Med 10 (1):95-112. PMID: 20205682 (2009)
Evolutionary game theory elucidates the role of glycolysis in glioma progression and invasion
Basanta D, Simon M, Hatzkikirou H, Deutsch A
Cell Proliferation 41 (6) 980, PMID: 19040573 (2008)
The Evolution of Robust Development and Homeostasis in Artificial Organism
Basanta D, Miodownik M, Baum B
PLoS Comput Biol 4(3) PMCID: PMC2274883
Studying the emergence of invasiveness in tumours using game theory
Basanta D, Hatzikirou H, Deutsch A
European Physical Journal B 63 (3) 393-397 (2008)