Bernhard Trinczek

Research Associate

Molecular Biology, Protein Chemistry, Biochemistry


Publications

  • Berndt N, Yang H, Trinczek B, Betzi S, Zhang Z, Wu B, Lawrence NJ, Pellecchia M, Schönbrunn E, Cheng JQ, Sebti SM. The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane. Cell Death Differ. 2010 May 21. Pubmed ID: 20489726
  • Mandelkow EM, Thies E, Trinczek B, Biernat J, Mandelkow E. ARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons. J Cell Biol. 2004 Oct 11;167(1):99-110. Epub 2004 Oct 4.PMID: 15466480
  • Trinczek B, Brajenovic M, Ebneth A, Drewes G. MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes. J Biol Chem. 2004 Feb 13;279(7):5915-23. Epub 2003 Nov 1.PMID: 14594945
  • Schönbrunn E, Phlippen W, Trinczek B, Sack S, Eschenburg S, Mandelkow EM, Mandelkow E. Crystallization of a macromolecular ring assembly of tubulin liganded with the
  • anti-mitotic drug podophyllotoxin. J Struct Biol. 1999 Dec 15;128(2):211-5.PMID: 10600574
  • Trinczek B, Ebneth A, Mandelkow EM, Mandelkow E. Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles. J Cell Sci. 1999 Jul;112 ( Pt 14):2355-67.PMID: 10381391
  • Ebneth A, Godemann R, Stamer K, Illenberger S, Trinczek B, Mandelkow E. Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease. J Cell Biol. 1998 Nov 2;143(3):777-94.PMID: 9813097
  • Illenberger S, Zheng-Fischhöfer Q, Preuss U, Stamer K, Baumann K, Trinczek B, Biernat J, Godemann R, Mandelkow EM, Mandelkow E. The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease. Mol Biol Cell. 1998 Jun;9(6):1495-512.PMID: 9614189
  • Illenberger S, Drewes G, Trinczek B, Biernat J, Meyer HE, Olmsted JB, Mandelkow EM, Mandelkow E. Phosphorylation of microtubule-associated proteins MAP2 and MAP4 by the protein kinase p110mark. Phosphorylation sites and regulation of microtubule dynamics.J Biol Chem. 1996 May 3;271(18):10834-43.PMID: 8631898
  • Mandelkow EM, Schweers O, Drewes G, Biernat J, Gustke N, Trinczek B, Mandelkow E. Ann Structure, microtubule interactions, and phosphorylation of tau protein. N Y Acad Sci. 1996 Jan 17;777:96-106. Review.PMID: 8624133
  • Trinczek B, Biernat J, Baumann K, Mandelkow EM, Mandelkow E. Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules. Mol Biol Cell. 1995 Dec;6(12):1887-902.PMID: 8590813
  • Mandelkow EM, Biernat J, Drewes G, Gustke N, Trinczek B, Mandelkow E. Tau domains, phosphorylation, and interactions with microtubules. Neurobiol Aging. 1995 May-Jun;16(3):355-62; discussion 362-3. Review.PMID: 7566345
  • Drewes G, Trinczek B, Illenberger S, Biernat J, Schmitt-Ulms G, Meyer HE, Mandelkow EM, Mandelkow E. Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262. J Biol Chem. 1995 Mar 31;270(13):7679-88.PMID: 7706316
  • Gustke N, Trinczek B, Biernat J, Mandelkow EM, Mandelkow E. Domains of tau protein and interactions with microtubules. Biochemistry. 1994 Aug 16;33(32):9511-22.PMID: 8068626
  • Trinczek B, Marx A, Mandelkow EM, Murphy DB, Mandelkow E. Dynamics of microtubules from erythrocyte marginal bands. Mol Biol Cell. 1993 Mar;4(3):323-35.PMID: 8485321
  • Trinczek B, Robert-Nicoud M, Schwoch G. In situ localization of cAMP-dependent protein kinases in nuclear and chromosomal substructures: relation to transcriptional activity. Eur J Cell Biol. 1993 Feb;60(1):196-202.PMID: 8462595
  • Trinczek B, Schwoch G. Immunoelectron microscopical localization of the catalytic subunit of cAMP-dependent protein kinases in brain microtubules and neurofilaments. FEBS Lett. 1990 Dec 17;277(1-2):167-70.PMID: 2269349
  • Schwoch G, Trinczek B, Bode C. Localization of catalytic and regulatory subunits of cyclic AMP-dependent protein kinases in mitochondria from various rat tissues. Biochem J. 1990 Aug 15;270(1):181-8.PMID: 2396978

 

Bernhard Trinczek