PUBLICATIONS
2023
Maurin M, Ranjouri M, Megino-Luque C, Newberg JY, Du D, Martin K, Miner R III, Prater MS, Boon Wee DK, Centeno B, Pruett-Miller SM, Stewart P, Fleming JB, Yu X, Bravo-Cordero JJ, Guccione E, Black MA, Mann KM. RBFOX2 deregulation promotes pancreatic cancer progression and metastasis through alternative splicing. Nature Communications 2023 Dec 19; 14 (1): 8444. doi: 10.1038/s41467-023-44126-w.
2021
Aiderus A, Newberg JY, Guzman-Rojas L, Contreras-Sandoval AM, Meshey AL, Jones DJ, Amaya-Manzanares F, Rangel R, Ward JM, Lee SC, Ban KH, Rogers K, Rogers SM, Selvanesan L, McNoe LA, Copeland NG, Jenkins NA, Tsai KY, Black MA, Mann KM, Mann MB. Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression. PLoS Genet. 2021 Aug 16;17(8): e1009094. doi:10.1371/journal.pgen.1009094.
Aiderus A, Contreras-Sandoval AM, Meshey AL, Newberg JY, Ward JM, Swing DA, Copeland NG, Jenkins NA, Mann KM, Mann MB. Promoterless Transposon Mutagenesis Drives Solid Cancers via Tumor Suppressor Inactivation. Cancers (Basel), 2021 Jan 9;13(2):225. doi:10.3390/cancers13020225.
Ho JS, Di Tullio F, Schwarz M, Low D, Incarnato D, Gay F, Tabaglio T, Zhang J, Wollmann H, Chen L, An O, Chan THM, Hall Hickman A, Zheng S, Roudko V, Chen S, Karz A, Ahmed M, He HH, Greenbaum BD, Oliviero S, Serresi M, Gargiulo G, Mann KM, Hernando E, Mulholland D, Marazzi I, Wee DKB, Guccione E. HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness. Elife. 2021 Jun 2;10: e59654 doi: 10.7554/eLife.59654.
2018
Newberg JY, Black MA Jenkins NA, Copeland NG, Mann KM, Mann MB. SB Driver Analysis: a Sleeping Beauty cancer driver analysis framework for identifying and prioritizing experimentally actionable oncogenes and tumor suppressors. Nucleic Acids Res, 2018 May 26;
Newberg JY, Mann KM, Mann MB, Jenkins NA and Copeland NG. SBCDDB: Sleeping Beauty Cancer Driver Database for gene discovery in mouse models of human cancers. Nucleic Acids Res, 2018 Jan; 46(D1): D1011-D1017
Mann KM, Newberg JY, Black MA, Jones DJ, Amaya-Manzanares F, Guzman-Rojas L, Kodama T, Ward J, Rust AG, van der Weyden L, Chin KY, Waters J, Leung ML, Rogers K, Rogers SM, McNoe L, Selvanesan L, Navin N, Jenkins NA, Copeland NG, and Mann MB. Analyzing tumor heterogeneity and driver genes in single myeloid leukemia cells with SBCapSeq. Nature Biotechnology, 2016 Sep; 34(9):962-72.
Mann KM, Ying H, Juan J, Jenkins NA, Copeland NG. KRAS-related proteins in pancreatic cancer. Pharmacol Ther. 2016 Sep 3. pii: S0163-7258(16)30159-0.
Goh AM, Xue Y, Leushacke M, Li L, Wong JS, Chiam PC, Rahmat SA, Mann MB, Mann KM, Barker N, Lozano G, Terzian T, Lane DP. Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice. Oncotarget. 2015 Jul 20;6(20):17968-80
Mann MB, Jenkins NA, Copeland NG and Mann KM. Sleeping Beauty mutagenesis: exploiting forward genetic screens for cancer gene discovery. Current Opinion in Genetics and Development. 2014 Feb;24:16-22
Mann KM, Jenkins NA, Copeland NG and Mann MB. Transposon Insertional Mutagenesis Models of Cancer. Cold Spring Harb Protoc. 2014 Mar 1;2014(3)
Mann KM, Ward JM, Yew CC, Kovochich A, Dawson DW, Black MA, Brett BT, Sheetz TE, Dupuy AJ; Australian Pancreatic Cancer Genome Initiative, Chang DK, Biankin AV, Waddell N, Kassahn KS, Grimmond SM, Rust AG, Adams DJ, Jenkins NA, Copeland NG. Sleeping Beauty Mutagenesis Reveals Cooperating Mutations and Pathways in Pancreatic Adenocarcinoma. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):5934-41